Revalia Bio
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A new source of truth for human biology

We're using AI to transform donated human organs into
high-fidelity biological data, shared insight, and faster decisions.

Five Layers One Truth

Each layer of The Human Data Stack maps directly to a stage in the journey from raw biological signal to actionable clinical intelligence with AI embedded at every junction.

Generate

Transform donated organs into rich, multi-modal biological datasets.

Ingest

Capture real-time physiology, histories, and molecular insights across multi-length scales.

Integrate

Connect multi-dimensional human-derived datasets

Interpret

Apply foundational models to decode complex data.

Deliver

Provide decision-ready insights for drug & device development.

Unlocking theNext Generationof Medicine

Today, medicine still depends on models that only approximate human biology. That slows development, puts patient lives at risk, and leaves critical decisions to guesswork.

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Patients
Healthcare
Biotech
Pharma
Regulatory

The Human Data Stack

End-to-end infrastructure for generating, integrating, and delivering human-biology insight at scale.

Revalia AIRevalia AIIntegrateAnalyzeLearn
Safety Signals
Dose Selection
Target Selection
Patient Selection
PK/PD Profile
Biodistribution Profile
Mechanism of Action
Optimized Delivery
Safety Signals
Dose Selection
Target Selection
Patient Selection
PK/PD Profile
Biodistribution Profile
Mechanism of Action
Optimized Delivery
The Human Data Stack
About Us

Our Founding Story

Revalia was founded through the 10+ year relationship of Greg, Jenna, and Kourosh when they had the simple realization: organs don't have to be transplantable to be transformative.

2022

Founded

Revalia Bio founded by Yale scientists Greg Tietjen and Jenna DiRito

2023

Revenue Generated

Generated first revenue from human organ research services

2024

Raised Seed Round

Secured seed funding to scale the Human Data Stack platform

2025

Opened Organ ICU

Launched state-of-the-art Organ ICU facility for human data trials

Science First

Every decision anchored in rigorous scientific inquiry

Revenue from Day One

Built a sustainable business from the earliest stages

World-Class Infrastructure

Purpose-built facilities for human organ research at scale

Government Trust

Trusted by government agencies for critical health research

Our founding journey
Our founding journey timeline

Behind Every Discovery

Is a Gift of Hope

Our Promise

Dear Donors and Donor Families,

I want you to know that your decision — made in one of the most difficult moments of your life — carries a weight and a beauty that words can hardly capture. By choosing to donate, you have transformed your loss into a lifeline for others.

We hold your gift with the reverence it deserves. Every organ entrusted to Revalia is treated not as a specimen, but as a sacred trust — a piece of someone you loved deeply.

Working alongside organ procurement organizations and healthcare partners, we ensure that when an organ cannot save a life through transplant, it is given the chance to save thousands through discovery.

Your generosity lives on in every answer we find, every therapy we help create, and every patient whose life may one day be changed. You have given us the most profound gift — the chance to turn heartbreak into hope.

With deep gratitude and respect,

Greg Tietjen

Co-Founder & Chief Executive Officer

Greg Tietjen signature

In partnership with leading organ procurement organizations (OPOs) and healthcare institutions, we ensure every donor gift is handled with the highest ethical standards, transparency, and respect throughout its lifecycle.

Expertise Across the Full
Human Data Stack

From transplantation and translational science to AI, hardware, software, and operations.

Co-Founder & Chief Executive Officer
Greg Tietjen

Greg Tietjen

Former Assistant Professor at Yale; pioneer of human organ research

Co-Founder & Chief Operating Officer
Jenna DiRito

Jenna DiRito

World leading expert in human organ research operations

Chief Data Innovation Officer
Janeta Nikolovski

Janeta Nikolovski

Formerly with Johnson & Johnson, 25 yrs Research & Product Development across Pharma, Biotech, Med Device, Digital and Consumer Products

Co-Founder & Chief People Officer
Helen Hughes

Helen Hughes

Former Senior Executive at Amazon, 20 years creating high performance teams in rapid growth organizations

Co-Founder & Chief Executive Officer
Greg Tietjen

Greg Tietjen

Former Assistant Professor at Yale; pioneer of human organ research

Co-Founder & Chief Operating Officer
Jenna DiRito

Jenna DiRito

World leading expert in human organ research operations

Chief Data Innovation Officer
Janeta Nikolovski

Janeta Nikolovski

Formerly with Johnson & Johnson, 25 yrs Research & Product Development across Pharma, Biotech, Med Device, Digital and Consumer Products

Co-Founder & Chief People Officer
Helen Hughes

Helen Hughes

Former Senior Executive at Amazon, 20 years creating high performance teams in rapid growth organizations

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✦Get Started

Bridge the Gap Between Biology & Breakthrough

Whether you're seeking information, sharing insights, or exploring potential collaborations, we value your time and look forward to hearing from you.

01Tell us about your program

Share your current challenges and goals

02Explore the Human Data Stack

See how our platform can address your needs

03Design a partnership

Build a custom solution for your pipeline


Recent Press

Front-Loading Drug Development: Q&A with Jenna DiRito, PhD, Revalia Bio

Front-Loading Drug Development: Q&A with Jenna DiRito, PhD, Revalia Bio


Applied Clinical Trials

April 16, 2026

Regulatory setback or scientific signal? The case for human-relevant evidence

Regulatory setback or scientific signal? The case for human-relevant evidence


pharmaphorum

Mar 26, 2026

How human organs are rewriting the rules of drug development

How human organs are rewriting the rules of drug development


Drug and Device World

Mar 17, 2026

Meet the Class of 2026 TED Fellows

Meet the Class of 2026 TED Fellows


TED

Mar 3, 2026

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Join UsDecodingHuman Biology

We're building a new category at the intersection of biology, AI, and infrastructure.

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RevaliaBio

Decoding human biology through donated organs, AI-enabled data systems, and cross-functional collaboration.

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Building the future of medicine.